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Bioorganic and Medicinal Chemistry 52,116517

Macrocyclic BACE1 inhibitors with hydrophobic cross-linked structures: Optimization of ring size and ring structure
DOI: 10.1016/j.bmc.2021.116517

Biochemical and Biophysical Research Communications 581, pp. 103-109

Human hepatitis B virus-derived virus-like particle as a drug and DNA delivery carrier
DOI: 10.1016/j.bbrc.2021.10.009

Diabetologia 64(12), pp. 2803-2816
(Open Access)

Characterisation of Ppy-lineage cells clarifies the functional heterogeneity of pancreatic beta cells in mice
DOI: 10.1007/s00125-021-05560-x

Inhibition of Gli2 suppresses tumorigenicity in glioblastoma stem cells derived from a de novo murine brain cancer model
DOI: 10.1038/s41417-020-00282-5

Bioorganic and Medicinal Chemistry 52,116496

Development of novel radioiodinated exendin-4 derivatives targeting GLP-1 receptor for detection of β-cell mass
DOI: 10.1016/j.bmc.2021.116496

放射性同位元素研究センター
河嶋 秀和 先生

Journal of Pharmaceutical Sciences 110(12), pp. 3937-3945

Liposomalization of Oxaliplatin Exacerbates the Non-Liposomal Formulation-Induced Decrease of Sweet Taste Sensitivity in Rats
DOI: 10.1016/j.xphs.2021.07.004

Scientific Reports 11(1),22919
(Open Access)

Pax5 mediates the transcriptional activation of the CD81 gene
DOI: 10.1038/s41598-021-02082-9

Cell Death Discovery 7(1),360
(Open Access)

A novel endoplasmic stress mediator, Kelch domain containing 7B (KLHDC7B), increased Harakiri (HRK) in the SubAB-induced apoptosis signaling pathway
DOI: 10.1038/s41420-021-00753-0

Journal of Pharmaceutical Health Care and Sciences 7(1),38
(Open Access)

Bibliometric analysis of pharmacist’s research on antimicrobial stewardship in Japan: an interrupted time series analysis on the implementation of the certification system for infection control pharmacists
DOI: 10.1186/s40780-021-00223-w

Journal of Cellular Biochemistry 122(12), pp. 1958-1967

Functional differences between Hsp105/110 family proteins in cell proliferation, cell division, and drug sensitivity
DOI: 10.1002/jcb.30158

BMC Health Services Research 21(1),1118
(Open Access)

Effects of the cefazolin shortage on the sales, cost, and appropriate use of other antimicrobials
DOI: 10.1186/s12913-021-07139-z

BMC Infectious Diseases 21(1),983
(Open Access)

Trends in healthcare visits and antimicrobial prescriptions for acute infectious diarrhea in individuals aged 65 years or younger in Japan from 2013 to 2018 based on administrative claims database: a retrospective observational study
DOI: 10.1186/s12879-021-06688-2

Journal of Infection and Chemotherapy,  27(12), pp. 1723-1728

Incidence of acute kidney injury after teicoplanin– or vancomycin– and piperacillin/tazobactam combination therapy: A comparative study using propensity score matching analysis
DOI: 10.1016/j.jiac.2021.08.012

Cancers 13(24),6382
(Open Access)

Population pharmacokinetic model-based evaluation of intact oxaliplatin in rats with acute kidney injury
DOI: 10.3390/cancers13246382

Scientific Reports 11(1),16276
(Open Access)

Juvenile social defeat stress exposure favors in later onset of irritable bowel syndrome-like symptoms in male mice
DOI: 10.1038/s41598-021-95916-5

Scientific Reports 11(1),15014
(Open Access)

Distinctive detection of insulinoma using [18F]FB(ePEG12)12-exendin-4 PET/CT
DOI: 10.1038/s41598-021-94595-6

Drug Development Research 82(8), pp. 1235-1246

A quinazoline-based bromodomain inhibitor, CN210, ameliorates indomethacin-induced ileitis in mice by inhibiting inflammatory cytokine expression
DOI: 10.1002/ddr.21838

BMC Cancer 21(1),304
(Open Access)

The role of EORTC QLQ-C15-PAL scores and inflammatory biomarkers in predicting survival in terminally ill patients with cancer
DOI: 10.1186/s12885-021-08049-3

Journal of Pharmaceutical Health Care and Sciences 7(1),8
(Open Access)

Effectiveness of protocol-based pharmacotherapy management collaboration between hospital and community pharmacists to address capecitabine-related hand–foot syndrome in cancer patients: a retrospective study
DOI: 10.1186/s40780-021-00191-1

Scientific Reports 11(1),2616
(Open Access)

Src-mediated tyrosine phosphorylation of PRC1 and kinastrin/SKAP on the mitotic spindle
DOI: 10.1038/s41598-021-82189-1

Nature Communications 12(1),404
(Open Access)

Enantioselective preparation of mechanically planar chiral rotaxanes by kinetic resolution strategy
DOI: 10.1038/s41467-020-20372-0

Journal of Neuroendocrinology 33(12), e13057
(Open Access)

Conditional ablation of vasopressin-synthesizing neurons in transgenic rats
DOI: 10.1111/jne.13057