お知らせ一覧

CN470 is a BET/CBP/p300 multi-bromodomain inhibitor and has an anti-tumor activity against MLL-rearranged acute lymphoblastic leukemia
DOI: 10.1016/j.bbrc.2021.12.078

Biochemical and Biophysical Research Communications 588, pp. 147-153

The CDK4/6-UCHL5-BRD4 axis confers resistance to BET inhibitors in MLL-rearranged leukemia cells by suppressing BRD4 protein degradation
DOI: 10.1016/j.bbrc.2021.12.063

Biochemical and Biophysical Research Communications 588, pp. 47-54

Expression level of BTN3A1 on the surface of CD14+ monocytes is a potential predictor of γδ T cell expansion efficiency
DOI: 10.1016/j.bbrc.2021.12.060

Life Sciences 289,120217

Dextran sulfate sodium-induced colitis in C57BL/6J mice increases their susceptibility to chronic unpredictable mild stress that induces depressive-like behavior
DOI: 10.1016/j.lfs.2021.120217

Organic and Biomolecular Chemistry 20(1), pp. 196-207

Construction of sulfur-containing compounds with anti-cancer stem cell activity using thioacrolein derived from garlic based on nature-inspired scaffolds
DOI: 10.1039/d1ob01992a

European Journal of Pharmacology 914,174681

Secreted protein acidic and rich in cysteine(SPARC) and a disintegrin and metalloproteinase with thrombospondin type 1 motif (ADAMTS1) increments by the renin-angiotensin system induce renal fibrosis in deoxycorticosterone acetate-salt hypertensive rats
DOI: 10.1016/j.ejphar.2021.174681

Antioxidants 11(1),43

Preventive effects of β-cryptoxanthin, a potent antioxidant and provitamin a carotenoid, on lifestyle-related diseases—a central focus on its effects on non-alcoholic fatty liver disease (Nafld)
DOI: 10.3390/antiox11010043

Journal of Functional Foods 88,104907

Prevention of tumor progression in inflammation-related carcinogenesis by anti-inflammatory and anti-mutagenic effects brought about by ingesting fermented brown rice and rice bran with Aspergillus oryzae (FBRA)
DOI: 10.1016/j.jff.2021.104907

Nutrients14(1),21

Exercise performance upregulatory effect of r-α-lipoic acid with γ-cyclodextrin
DOI: 10.3390/nu14010021

Fitoterapia156,105097

Chemical structures and induction of cell death via heat shock protein inhibition of the prenylated phloroglucinol derivatives isolated from Hypericum erectum
DOI: 10.1016/j.fitote.2021.105097

Supportive Care in Cancer30(1), pp. 135-143

Symptom clusters and their influence on prognosis using EORTC QLQ-C15-PAL scores in terminally ill patients with cancer
DOI: 10.1007/s00520-021-06380-w

Cancer Gene Therapy 29(1), pp. 37-48

γ-Glutamylcyclotransferase, a novel regulator of HIF-1α expression, triggers aerobic glycolysis