1. Pharmacological research targeting mast cells
    (1) Regulation of mast cell functions through its differentiation
    (2) G protein-coupled receptors-mediated modulation of mast cell functions
    (3) Exploration of novel physiological roles of mast cells


2. Development of novel therapeutic drugs for itch and skin barrier dysfunction in atopic dermatitis
    (1)  Identification of the responsible molecule(s) of atopic dermatitis-associated itch
    (2)  Pharmacological analysis of the mechanisms underlying central regulation of itch in atopic dermatitis model mice
    (3) Elucidation of the mechanism of improvement of skin barrier function by polyunsaturated fatty acids